The Mannich Reaction of Alicyclic α-Diketones. A Novel Synthesis of 2-Hydroxy-3-methyl-2-cyclohexen-1-one

Mannich Reaction with 5,5-Dimethyl-3-phenylamino-2-cyclohexen-l-one

W. S. Hamama, M. Hammouda*, and E. M. Afsah Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt Z. Naturforsch. 43b, 483-486 (1988); received August 18, 1986/October 26, 1987 Mannich Bases of Enaminones, Octahydro-9H-pyrimido[5,4-b]-azepines, Tetrahydro-4H-[3,l]benzoxazin-5(6H)-one, Nitrogen Heterocycles Mannich reaction of the title compound 1 with morpholine, piperi...

Synthesis of 1-Hydroxy-2-(Prop-2'-Enyl) 9-Antrone

An efficient synthesis of the 1-hydroxy-2-(prop-2'-enyl)9-anthrone is described. Selective nitration of anthraquinone, reduction to the corresponding amine, diazotization and treatment by sulfuric acid solution afforded the 1-hydroxy-9,10-anthraquinone in good yield as the key intermediate. Reaction with allyl bromide/K2CO3 and subsequent selective reduction accompanie...

SYNTHESIS OF OXAZOLO [3, 2-b] 1, 2, 4- TRIAZINES A NOVEL HETEROCYCLIC SYSTEM

The synthesis of 6- methyl- 2- phenyl- 7H- oxazolo [3,2-b] 1,2,4-Triazine- 7-one (6, R=Ph) and its 2-P- bromophenyl analogue to the two members of a new heterocyclic system is described

a straightforward synthesis of imidazoisoindole-5-one via one-pot reaction of 1, 2-diketones, 2-formylbenzoic acids and ammonium acetate

Synthesis and Valuation of Mannich Bases of Certain Novel Nitro Hydroxy 1, 2 – Pyrazolines

A study was conducted to synthesise and evaluate the anti-inflammatory and anti-microbial activities of mannich bases from 1, 2 - hydroxy pyrazolines. For this, vanillin was reacted with substituted acetophenones and different vanillinyl chalcones were obtained which when coupled with phenyl hydrazine, produced hudroxy 1, 2 - pyrazolines. The hydroxyl pyrazolines were reacted with sulpha drugs ...